Two men have died after a serious crash on the M40.
Officers attended the scene along with the ambulance service, fire service and Highways England.
Two men, a 60-year-old man from Oxfordshire and a 29-year-old man from Warwickshire, have sadly died as a result of the collision. One man was taken to hospital with serious leg injuries and three others were treated for minor injuries.
The next of kin for both victims have been informed and are being supported by specially trained officers.
The road was closed between junction 10, Cherwell Valley Services, and junction 11, Banbury but has since been reopened.
Chief Inspector Henry Parsons from the Joint Operations Unit for Roads Policing, said: “Our thoughts are with both men’s families at this difficult time. We would like to speak to anyone who may have witnessed the collision who has not yet spoken to police.
“We would appeal to anyone who witnessed the collision and has not yet spoken to officers to please contact us. Anyone who has any information which could assist the investigation should call the 24-hour Thames Valley Police enquiry centre on 101 quoting URN 1669 (23/12)."
If you have any information relating to this case, please call 101 quoting reference '1669 (23/12)', or contact Crimestoppers anonymously.